Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5939825 | 0.85 | PRSS1 (0.55) | MAPTLMNAALDH1A1EPHX2ESRRG | |
| SCHEMBL9659945 | 0.84 | LMNA (0.57) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL28795015 | 0.81 | ALDH1A1 (0.55) | HIF1AALDH1A1EPHX2BLMKMT2A | |
| SCHEMBL854839 | 0.78 | MAPT (0.63) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL5119130 | 0.77 | KDM4E (0.58) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL19302966 | 0.77 | EPHX2 (0.55) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL1290599 | 0.75 | LMNA (0.68) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| Dimethylamine SCHEMBL6108538 | 0.75 | MAPT (0.59) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL10545735 | 0.75 | KDM4E (0.59) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL10874011 | 0.74 | L3MBTL1 (0.46) | LMNAALDH1A1MAPK1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102449165-B | Genetic markers for risk management of atrial fibrillation and stroke | DECODE GENETICS EHF | 2014-07-09 | — | — | CN | disclosed |
| CN-102449165-A | Genetic markers for risk management of atrial fibrillation and stroke | DECODE GENETICS EHF | 2012-05-09 | — | — | CN | disclosed |