SCHEMBL27873333

SCHEMBL27873333

C=C[SiH2]C1(CCc2ccccc2)CCCCO1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.31
OPRL1 P41146 2/20 0.31
KDM1A O60341 2/20 0.31
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27294479 0.86 MAOA (0.35) MAOAMAOB
SCHEMBL28042664 0.74
SCHEMBL27586838 0.73 ALDH1A1 (0.35) OPRM1OPRL1L3MBTL1ALDH1A1
SCHEMBL11278654 0.71
SCHEMBL4352239 0.71
SCHEMBL27615991 0.71
SCHEMBL27537081 0.71
SCHEMBL477537 0.70 KDM1A (0.35) OPRM1OPRL1KDM1AMAOAMAOB
SCHEMBL463561 0.69 MEN1 (0.31) L3MBTL1ALDH1A1
SCHEMBL9694869 0.69 MAOA (0.38) OPRM1OPRL1MAOAMAOBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102686647-B Method of producing aramid silicone polymer DOW CORNING TORAY CO LTD 2014-05-21 CN disclosed
CN-102686647-A Method of producing aramid silicone polymer DOW CORNING TORAY CO LTD 2012-09-19 CN disclosed