SCHEMBL477537

SCHEMBL477537

[SiH3]C1(CCc2ccccc2)CCCCO1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.35
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
OPRM1 P35372 9/20 0.35
OPRL1 P41146 2/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338864 0.90 SIGMAR1 (0.37) MAOAOPRM1OPRL1
SCHEMBL16243044 0.89 OPRM1 (0.37) MAOAMAOBOPRM1OPRL1
SCHEMBL60702 0.83 MAOA (0.41) KDM1AMAOAMAOBOPRM1OPRL1
SCHEMBL27668036 0.81 MAOA (0.40) KDM1AMAOAMAOBOPRM1OPRL1
SCHEMBL28548973 0.81 CYP3A4 (0.30)
SCHEMBL28605731 0.78
SCHEMBL1310184 0.77 OPRM1 (0.45) OPRM1ALDH1A1
SCHEMBL27820384 0.77 ALDH1A1 (0.33) ALDH1A1
SCHEMBL11758570 0.76 MAOA (0.35) MAOAMAOBOPRM1ALDH1A1
SCHEMBL9222671 0.76 HTR2A (0.37) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116510692-A Magnetic nano adsorbent, preparation method and application thereof 广东工业大学 2023-08-01 CN claimed
CN-112521577-B High-toughness polyurethane grouting material and preparation method thereof 无锡琛华复合材料有限公司 2022-09-13 CN claimed
CN-114792589-A High-strength organosilicon silicon rubber disc-shaped suspension type porcelain and glass composite insulator 王福有 2022-07-26 CN claimed
CN-112521577-A High-toughness polyurethane grouting material and preparation method thereof 无锡琛华复合材料有限公司 2021-03-19 CN claimed
CN-105324551-A Treatment for non-caking mine rock dust IMERYS PIGMENTS INC 2016-02-10 CN claimed
EP-2283064-A1 SULFONATED POLY 2-(PHENYL ETHYL) SILOXANE POLYMER ELECTROLYTE MEMBRANES University Of Ontario Institute Of Technology (CA) 2011-02-16 EP claimed
WO-2009140773-A1 SULFONATED POLY 2-(PHENYL ETHYL) SILOXANE POLYMER ELECTROLYTE MEMBRANES UNIVERSITY OF ONTARIO INSTITUTE OF TECHNOLOGY (CA) 2009-11-26 WO claimed
CN-117903696-A Water-based modified fluorosilicone resin coating composition, coating and preparation method thereof 东莞市雄驰电子有限公司 2024-04-19 CN disclosed
EP-2559534-B1 Composition and method for casting manufacturing RAYTHEON TECH CORP (US) 2023-10-25 EP disclosed
CN-116510692-A Magnetic nano adsorbent, preparation method and application thereof 广东工业大学 2023-08-01 CN disclosed
CN-112521577-B High-toughness polyurethane grouting material and preparation method thereof 无锡琛华复合材料有限公司 2022-09-13 CN disclosed
CN-114792589-A High-strength organosilicon silicon rubber disc-shaped suspension type porcelain and glass composite insulator 王福有 2022-07-26 CN disclosed
CN-112521577-A High-toughness polyurethane grouting material and preparation method thereof 无锡琛华复合材料有限公司 2021-03-19 CN disclosed
US-4476291-A Resins containing β-phenylethyl trifunctional siloxy units and method for making GENERAL ELECTRIC COMPANY (US) 1984-10-09 US disclosed
EP-0061694-B1 ANTIFREEZE CONCENTRATE AND COOLANT FOR COOLING SYSTEMS OF INTERNAL COMBUSTION ENGINES, CONTAINING COPOLYMERS OF AN ORGANO SILICONE SULFONATE AND A SILICATE BASF WYANDOTTE CORPORATION (US) 1984-02-01 EP disclosed
US-4362644-A Arylalkyl silicone sulfonate-silicate copolymers BASF WYANDOTTE CORPORATION (US) 1982-12-07 US disclosed
EP-0061694-A1 Antifreeze concentrate and coolant for cooling systems of internal combustion engines, containing copolymers of an organo silicone sulfonate and a silicate BASF WYANDOTTE CORPORATION (US) 1982-10-06 EP disclosed
US-4312693-A TREATMENT OF SILICONE RUBBER WITH GAS PLASMA AT LOW PRESSURE UNION CARBIDE CORPORATION (US) 1982-01-26 US disclosed
US-4070313-A PHENOLIC RESOLE, BLOWING AGENT, POLYSILOXANE UNION CARBIDE CORPORATION (US) 1978-01-24 US disclosed
US-3957715-A SILICONE RESIN HOWMET CORPORATION (US) 1976-05-18 US disclosed