SCHEMBL9694869

SCHEMBL9694869

C[SiH2]C1(Cc2ccccc2)CCCCO1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
GAA P10253 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
OPRL1 P41146 3/20 0.33
OPRM1 P35372 2/20 0.33
OPRK1 P41145 1/20 0.33
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27586838 0.82 ALDH1A1 (0.35) L3MBTL1OPRL1OPRM1OPRK1
SCHEMBL27294479 0.80 MAOA (0.35) MAOAMAOBTSHR
SCHEMBL28273955 0.80
SCHEMBL7019392 0.78 MAOA (0.33) MAOAMAOB
SCHEMBL28103383 0.76 TAAR1 (0.35) OPRM1
SCHEMBL19466530 0.76 MMP2 (0.33) MAOAMAOB
SCHEMBL28187490 0.73
SCHEMBL28350310 0.73 ALDH1A1 (0.32) L3MBTL1TSHR
Ammonia Solution, Strong SCHEMBL4767628 0.73 MAOA (0.42) MAOAMAOBKMT2AOPRL1OPRM1
SCHEMBL5685184 0.72 MAOA (0.39) MAOAMAOBGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0468626-A2 Cotton bales and method of producing same Takemoto Yushi Kabushiki Kaisha (JP) 1992-01-29 EP disclosed