Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27874050 | 0.82 | GAA (0.40) | DRD2DRD3GAAGFERALDH1A1 | |
| SCHEMBL2330967 | 0.80 | POLB (0.43) | DRD2POLBGAAGFERALDH1A1 | |
| SCHEMBL3153019 | 0.79 | HTR1A (0.49) | DRD2GAAGFERALDH1A1L3MBTL1 | |
| SCHEMBL123592 | 0.77 | POLB (0.71) | POLBALDH1A1 | |
| SCHEMBL27793409 | 0.73 | POLB (0.47) | POLBGAAGFERALDH1A1L3MBTL1 | |
| SCHEMBL3153025 | 0.71 | ADRA1A (0.46) | DRD2DRD3GAAGFERALDH1A1 | |
| SCHEMBL27814629 | 0.71 | GAA (0.52) | DRD2GAAGFERALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2337988 | 0.70 | ADRA1A (0.45) | DRD2DRD3GAAGFERALDH1A1 | |
| SCHEMBL3693484 | 0.70 | SMN1; SMN2 (0.49) | POLBGAAALDH1A1 | |
| SCHEMBL12156788 | 0.70 | DRD2 (0.54) | DRD2DRD3POLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101790522-B | Substituted piperazinylpyrazines and pyridines as 5-HT7Receptor antagonists | LILLY CO ELI | 2012-06-27 | — | — | CN | disclosed |