Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3774666 | 0.92 | LMNA (0.42) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL16882299 | 0.92 | LMNA (0.42) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL3774606 | 0.92 | LMNA (0.42) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL14463170 | 0.82 | ALDH1A1 (0.47) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL5202981 | 0.80 | ALDH1A1 (0.45) | SMN1; SMN2LMNAALDH1A1ATMTSHR | |
| SCHEMBL4719492 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL7114208 | 0.79 | NPSR1 (0.37) | LMNACYP2C19CYP3A4CYP2C9 | |
| SCHEMBL24325993 | 0.78 | NAAA (0.47) | LMNAALDH1A1TSHRESR1RAB9A | |
| Formic Acid SCHEMBL28786714 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL28491047 | 0.76 | ALDH1A1 (0.42) | SMN1; SMN2LMNAPOLBALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097374-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |