Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1939405 | 0.84 | CA2 (0.35) | LOXL2ADORA3SLC6A3 | |
| SCHEMBL3474793 | 0.75 | ADORA3 (0.55) | LOXL2KDM4EADORA3SLC6A3TSHR | |
| SCHEMBL5875752 | 0.74 | ADORA3 (0.67) | LOXL2ADORA3SLC6A3TSHRLOX | |
| Hydrochloric Acid SCHEMBL28327830 | 0.73 | ADORA3 (0.53) | LOXL2KDM4EADORA3SLC6A3TSHR | |
| SCHEMBL5875686 | 0.73 | ADORA3 (0.49) | LOXL2KDM4EADORA3SLC6A3SMN1; SMN2 | |
| SCHEMBL1348269 | 0.72 | KDM4E (0.32) | LOXL2KDM4EADORA3SLC6A3 | |
| SCHEMBL5875742 | 0.71 | ADORA3 (0.47) | LOXL2ADORA3SLC6A3SMN1; SMN2LOX | |
| SCHEMBL2823118 | 0.71 | LMNA (0.39) | LOXL2KDM4EADORA3SLC6A3SMN1; SMN2 | |
| SCHEMBL15865702 | 0.71 | HCAR2 (0.45) | LOXL2KDM4EADORA3SLC6A3LOX | |
| SCHEMBL1941169 | 0.70 | ALOX5AP (0.39) | LOXL2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102725272-B | Synthesis of substituted pyrazoline carboxamidine derivatives | ABBOTT HEALTHCARE PRODUCTS BV | 2015-07-15 | — | — | CN | disclosed |
| CN-102725272-A | Synthesis of substituted pyrazoline carboxamidine derivatives | ABBOTT HEALTHCARE PRODUCTS BV | 2012-10-10 | — | — | CN | disclosed |