Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | BRS3 | P32247 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | PPM1D | O15297 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28174259 | 0.95 | BRS3 (0.41) | ALDH1A1KMT2AKDM5BKDM5ABRS3 | |
| SCHEMBL28165784 | 0.91 | ALDH1A1 (0.44) | ALDH1A1BRS3KDM4CALOX15 | |
| SCHEMBL28175595 | 0.83 | BRS3 (0.46) | ALDH1A1KMT2ABRS3EPHX2KDM4C | |
| SCHEMBL7298560 | 0.81 | PPM1D (0.53) | ALDH1A1KMT2AKDM5BKDM5ABRS3 | |
| SCHEMBL10790692 | 0.80 | HMGB1 (0.51) | ALDH1A1KMT2AKDM5BKDM5ABRS3 | |
| SCHEMBL27875223 | 0.80 | CCR3 (0.38) | ALDH1A1KDM5BKDM5AKDM4CALOX15 | |
| SCHEMBL2468476 | 0.79 | MMP2 (0.49) | ALDH1A1BRS3NPC1RAB9AALOX15 | |
| SCHEMBL28074770 | 0.77 | SLC6A1 (0.46) | ALDH1A1KMT2A | |
| SCHEMBL12482994 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL2751335 | 0.76 | KDM5B (0.49) | ALDH1A1KMT2AKDM5BKDM5ABRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458883-A | Chlorine resistant polyethylene compounds and articles made therefrom | 弗纳技术股份有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106983751-A | Two ring substituted uracils and application thereof | 拜耳医药股份有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-104395310-B | Bicyclic substituted uracils and their use | 拜耳药业股份公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-106574114-A | Curable organopolysiloxane compositions | 瓦克化学股份公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-106458883-A | Chlorine resistant polyethylene compounds and articles made therefrom | 弗纳技术股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-104370909-A | Novel tricyclic compounds | ABBOTT LAB | 2015-02-25 | — | — | CN | disclosed |
| CN-102711476-B | Novel tricyclic compounds | ABBVIE LAB | 2014-12-03 | — | — | CN | disclosed |
| CN-102712640-A | Tricyclic heterocyclic compounds, compositions and methods of use thereof | HOFFMANN LA ROCHE | 2012-10-03 | — | — | CN | disclosed |
| CN-102711476-A | Novel tricyclic compounds | ABBOTT LAB | 2012-10-03 | — | — | CN | disclosed |
| CN-100362026-C | Process for producing catalyst for olefin polymerization and process for producing olefin polymer | SUMITOMO CHEMICAL CO (JP) | 2008-01-16 | — | — | CN | disclosed |
| CN-1232544-C | Process for producing catalyst for olefin polymerization and process for producing olefin polymer | SUMITOMO CHEMICAL CO (JP) | 2005-12-21 | — | — | CN | disclosed |
| CN-1690091-A | Process for producing catalyst for olefin polymerization and process for producing olefin polymer | SUMITOMO CHEMICAL CO (JP) | 2005-11-02 | — | — | CN | disclosed |
| CN-1316442-A | Process for producing catalyst for olefin polymerization and process for producing olefin polymer | SUMITOMO CHEMICAL CO (JP) | 2001-10-10 | — | — | CN | disclosed |