Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 10/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785339 | 0.84 | HIF1A (0.45) | KDRKITFLT3MEN1KMT2A | |
| SCHEMBL2786010 | 0.76 | CYP1A2 (0.43) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL2770206 | 0.74 | GAA (0.51) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2784439 | 0.72 | KIT (0.39) | KDRKITFLT3MAPTLMNA | |
| SCHEMBL2785082 | 0.71 | NPC1 (0.55) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL2783769 | 0.71 | USP2 (0.36) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL2785840 | 0.70 | NOX1 (0.36) | KDRKITFLT3MAPTNPC1 | |
| SCHEMBL2785719 | 0.70 | AURKB (0.42) | KDRKITFLT3MAPTNPC1 | |
| SCHEMBL2785205 | 0.69 | ALDH1A1 (0.38) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL2787147 | 0.69 | BRAF (0.49) | KDRKITFLT3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881967-B1 | SUBSTITUTED BENZO(D)ISOXAZOL-3-YL AMINE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2010-04-28 | — | — | EP | claimed |