Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.35 |
| ▸ | MVD | P53602 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28826381 | 0.77 | DPP4 (0.40) | DPP4 | |
| SCHEMBL29091403 | 0.74 | DPP4 (0.34) | DPP4 | |
| SCHEMBL27857100 | 0.74 | ALDH1A1 (0.39) | DPP4ALDH1A1 | |
| SCHEMBL27879615 | 0.74 | PREP (0.35) | NAMPTHCRTR2DPP4 | |
| SCHEMBL19104795 | 0.73 | SMN1; SMN2 (0.44) | HCRTR2DPP4ACE | |
| SCHEMBL28801602 | 0.73 | PREP (0.42) | HCRTR2DPP4 | |
| SCHEMBL7710658 | 0.73 | DPP4 (0.45) | MVDOPRM1DPP4ACE | |
| SCHEMBL27879636 | 0.72 | CHRM2 (0.37) | DPP4 | |
| SCHEMBL28232406 | 0.72 | HSD17B10 (0.47) | ALDH1A1 | |
| SCHEMBL27896393 | 0.71 | GAA (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |