Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896408 | 0.87 | MC4R (0.48) | ALDH1A1POLBHPGDHSD11B1 | |
| SCHEMBL27879645 | 0.78 | SIGMAR1 (0.45) | ALDH1A1POLB | |
| SCHEMBL3139945 | 0.76 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1POLBHPGD | |
| SCHEMBL5740374 | 0.76 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1POLBHPGD | |
| SCHEMBL27879616 | 0.76 | HRH3 (0.49) | ALDH1A1POLB | |
| SCHEMBL27896416 | 0.75 | MEN1 (0.46) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL27879623 | 0.75 | KMT2A (0.48) | ALDH1A1HPGD | |
| SCHEMBL29091403 | 0.73 | DPP4 (0.34) | POLB | |
| SCHEMBL28826381 | 0.73 | DPP4 (0.40) | POLB | |
| SCHEMBL27879615 | 0.73 | PREP (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |