Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.48 |
| ▸ | MC3R | P41968 | 2/20 | 0.48 |
| ▸ | MC1R | Q01726 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879612 | 0.87 | SMN1; SMN2 (0.57) | ALDH1A1POLBHPGDHSD11B1 | |
| SCHEMBL27879645 | 0.85 | SIGMAR1 (0.45) | DPP4ALDH1A1KDM4EPOLBPREP | |
| SCHEMBL27879616 | 0.82 | HRH3 (0.49) | ALDH1A1POLBPREP | |
| SCHEMBL10510159 | 0.80 | MC4R (0.52) | MC4RMC3RMC1RDPP4ALDH1A1 | |
| SCHEMBL10510105 | 0.80 | MC4R (0.52) | MC4RMC3RMC1RDPP4ALDH1A1 | |
| SCHEMBL27896416 | 0.80 | MEN1 (0.46) | ALDH1A1POLBL3MBTL1 | |
| SCHEMBL27879637 | 0.77 | CTSS (0.42) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL27896376 | 0.77 | ALDH1A1 (0.48) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL27879608 | 0.77 | CYP3A4 (0.42) | DPP4POLBHPGDHSD11B1PREP | |
| SCHEMBL5680028 | 0.76 | MC4R (0.54) | MC4RMC3RMC1RALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |