Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896408 | 0.82 | MC4R (0.48) | ALDH1A1POLBPREP | |
| SCHEMBL27896392 | 0.81 | GFER (0.50) | ALDH1A1MEN1KMT2APREP | |
| SCHEMBL13570735 | 0.79 | SPHK1 (0.53) | HRH3SIGMAR1OPRK1PARP1MEN1 | |
| SCHEMBL27879623 | 0.78 | KMT2A (0.48) | ALDH1A1SIGMAR1MEN1KMT2AGAA | |
| SCHEMBL27879645 | 0.76 | SIGMAR1 (0.45) | HRH3ALDH1A1SIGMAR1PARP1POLB | |
| SCHEMBL27879612 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1POLB | |
| SCHEMBL844898 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2A | |
| SCHEMBL27896410 | 0.73 | HPGD (0.50) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL13826659 | 0.72 | SIGMAR1 (0.60) | ALDH1A1SIGMAR1MEN1KMT2APOLB | |
| SCHEMBL16002968 | 0.71 | SIGMAR1 (0.62) | ALDH1A1SIGMAR1OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |