Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896515 | 0.80 | HSD17B10 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL27896408 | 0.80 | MC4R (0.48) | ALDH1A1POLBL3MBTL1 | |
| SCHEMBL6185857 | 0.78 | HRH3 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6184573 | 0.78 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6746536 | 0.78 | HRH3 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL27879612 | 0.75 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL27879607 | 0.75 | ADAM17 (0.41) | ALDH1A1SMN1; SMN2HTTADAM17POLB | |
| SCHEMBL27879645 | 0.74 | SIGMAR1 (0.45) | ALDH1A1SIGMAR1POLB | |
| SCHEMBL27879623 | 0.73 | KMT2A (0.48) | MEN1KMT2AALDH1A1SIGMAR1MAPT | |
| SCHEMBL7238470 | 0.72 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |