Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27837322 | 0.96 | GBA1 (0.50) | GBA1CYP11B2ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL2482820 | 0.94 | KDM4E (0.42) | GBA1CYP11B2ALDH1A1KDM4ECYP3A4 | |
| Hydrochloric Acid SCHEMBL5616198 | 0.93 | KDM4E (0.41) | GBA1CYP11B2ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL28759723 | 0.86 | CHRNB2 (0.41) | GBA1ALDH1A1KDM4ECHRNB2CHRNA4 | |
| SCHEMBL4037861 | 0.86 | CYP3A4 (0.39) | GBA1ALDH1A1KDM4ECYP3A4 | |
| Hydrochloric Acid SCHEMBL14119669 | 0.84 | KDM4E (0.58) | ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL9417424 | 0.82 | GBA1 (0.40) | GBA1CYP11B2ALDH1A1KDM4ECYP3A4 | |
| Hydrochloric Acid SCHEMBL10446673 | 0.80 | GBA1 (0.51) | GBA1CYP11B2ALDH1A1KDM4ECYP3A4 | |
| Hydrochloric Acid SCHEMBL27339224 | 0.80 | GBA1 (0.51) | GBA1CYP11B2ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL27837296 | 0.78 | CYP11B2 (0.50) | GBA1CYP11B2ALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102574845-A | 1h-imidazo[4,5-c]quinolinone derivatives | NOVARTIS AG | 2012-07-11 | — | — | CN | disclosed |