Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5616198 | 0.87 | KDM4E (0.41) | KDM4EALDH1A1CYP3A4 | |
| SCHEMBL2482820 | 0.85 | KDM4E (0.42) | KDM4EALDH1A1CYP3A4 | |
| SCHEMBL27879837 | 0.84 | GBA1 (0.47) | KDM4EALDH1A1CYP3A4 | |
| SCHEMBL27837322 | 0.81 | GBA1 (0.50) | KDM4EALDH1A1CYP3A4POLBSMN1; SMN2 | |
| SCHEMBL27669059 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1KDM4CHTR2AHTR2C | |
| SCHEMBL901151 | 0.79 | HTR2A (0.54) | KDM4EHTR2AHTR2CPOLBTSHR | |
| SCHEMBL28759723 | 0.78 | CHRNB2 (0.41) | KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4037861 | 0.78 | CYP3A4 (0.39) | KDM4EALDH1A1CYP3A4KDM4C | |
| Hydrochloric Acid SCHEMBL10446673 | 0.78 | GBA1 (0.51) | KDM4EALDH1A1CYP3A4HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL27339224 | 0.78 | GBA1 (0.51) | KDM4EALDH1A1CYP3A4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12472543-B2 | Waste disposal system and waste receiver for receiving and disposing of pharmaceutical waste material | STRYKER CORPORATION (US) | 2025-11-18 | — | — | US | disclosed |
| US-12434282-B2 | Pharmaceutical waste system | STRYKER CORPORATION (US) | 2025-10-07 | — | — | US | disclosed |
| US-20250268679-A1 | Waster Receiver For Receiving A Pharmaceutical Waste Material | STRYKER CORPORATION (US) | 2025-08-28 | — | — | US | disclosed |
| US-12318823-B2 | Waste receiver for receiving a pharmaceutical waste material | STRYKER CORPORATION (US) | 2025-06-03 | — | — | US | disclosed |
| US-20250144680-A1 | Pharmaceutical Waste Disposal Assembly | STRYKER CORPORATION (US) | 2025-05-08 | — | — | US | disclosed |
| EP-3902638-B1 | METHOD OF DISPOSING OF WASTE RECEIVER AND WASTE RECEIVER FOR PHARMACEUTICAL WASTE | STRYKER CORP (US) | 2025-02-26 | — | — | EP | disclosed |
| US-12194516-B2 | Pharmaceutical waste disposal assembly | STRYKER CORPORATION (US) | 2025-01-14 | — | — | US | disclosed |
| US-20240359222-A1 | Waste Receiver For Receiving A Pharmaceutical Waste Material | STRYKER CORPORATION (US) | 2024-10-31 | — | — | US | disclosed |
| US-12064797-B2 | Method of disposing of waste receiver, waste receiver for pharmaceutical waste and method of assembling the waste receiver | STRYKER CORPORATION (US) | 2024-08-20 | — | — | US | disclosed |
| US-20240066574-A1 | Waste Disposal System And Waste Receiver For Receiving And Disposing Of Pharmaceutical Waste Material | STRYKER CORPORATION (US) | 2024-02-29 | — | — | US | disclosed |
| US-20190126331-A1 | Waste Disposal System And Waste Receiver For Receiving And Disposing Of Pharmaceutical Waste Material | STRYKER CORPORATION (US) | 2019-05-02 | — | — | US | disclosed |
| US-20190084018-A1 | Pharmaceutical Waste Disposal Assembly | STRYKER CORPORATION (US) | 2019-03-21 | — | — | US | disclosed |
| WO-2019006346-A1 | WASTE DISPSAL SYSTEM AND WASTE RECEIVER FOR RECEIVING AND DISPOSING OF PHARMACEUTICAL WASTE MATERIAL | STRYKER CORPORATION (US) | 2019-01-03 | — | — | WO | disclosed |
| US-10086416-B2 | Pharmaceutical waste disposal assembly | STRYKER CORPORATION (US) | 2018-10-02 | — | — | US | disclosed |
| WO-2018049139-A2 | A PHARMACEUTICAL WASTE SYSTEM | STRYKER CORPORATION (US) | 2018-03-15 | — | — | WO | disclosed |
| US-20160325322-A1 | PHARMACEUTICAL WASTE DISPOSAL ASSEMBLY | STRYKER CORPORATION | 2016-11-10 | — | — | US | disclosed |
| US-9456954-B2 | Pharmaceutical waste disposal assembly | CACTUS, LLC (US) | 2016-10-04 | — | — | US | disclosed |
| US-9044377-B2 | Pharmaceutical waste disposal assembly | CACTUS, LLC (US) | 2015-06-02 | — | — | US | disclosed |
| US-20140190845-A1 | PHARMACEUTICAL WASTE DISPOSAL ASSEMBLY | CACTUS, LLC (US) | 2014-07-10 | — | — | US | disclosed |
| US-20120305132-A1 | PHARMACEUTICAL WASTE DISPOSAL ASSEMBLY | CACTUS, LLC. | 2012-12-06 | — | — | US | disclosed |