Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482820 | 0.88 | KDM4E (0.42) | CYP3A4GBA1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5616198 | 0.86 | KDM4E (0.41) | CYP3A4GBA1KDM4EALDH1A1 | |
| SCHEMBL27879837 | 0.86 | GBA1 (0.47) | CYP3A4GBA1KDM4EALDH1A1 | |
| SCHEMBL27837322 | 0.83 | GBA1 (0.50) | CYP3A4GBA1KDM4EALDH1A1MEN1 | |
| SCHEMBL28759723 | 0.81 | CHRNB2 (0.41) | GBA1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6575818 | 0.79 | NPC1 (0.42) | KDM4EMEN1KMT2AOPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL14119669 | 0.78 | KDM4E (0.58) | CYP3A4KDM4CKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10446673 | 0.74 | GBA1 (0.51) | CYP3A4GBA1KDM4EALDH1A1OPRM1 | |
| Hydrochloric Acid SCHEMBL27339224 | 0.74 | GBA1 (0.51) | CYP3A4GBA1KDM4EALDH1A1OPRM1 | |
| SCHEMBL9417424 | 0.74 | GBA1 (0.40) | CYP3A4GBA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555265-B1 | 7-PHENYL PYRAZOLOPYRIDINE COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2009-03-25 | — | — | EP | claimed |