Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 12/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1442275 | 0.91 | KDM4E (0.52) | WNT3AMAPTLMNATP53PORCN | |
| SCHEMBL1442679 | 0.91 | WNT3A (0.47) | WNT3AMAPTLMNATP53PORCN | |
| SCHEMBL27882033 | 0.90 | HTR1A (0.47) | WNT3AMAPTPORCN | |
| SCHEMBL10179313 | 0.89 | MAPT (0.52) | WNT3AMAPTLMNATP53KDM4E | |
| SCHEMBL1442321 | 0.89 | KARS1 (0.49) | WNT3AMAPTLMNATP53PORCN | |
| SCHEMBL27865624 | 0.87 | HTR1A (0.47) | WNT3AMAPTPORCNMAPK1 | |
| SCHEMBL10179752 | 0.86 | WNT3A (0.44) | WNT3AMAPTLMNATP53PORCN | |
| SCHEMBL10179379 | 0.86 | KDM4E (0.51) | WNT3AMAPTLMNATP53KDM4E | |
| SCHEMBL1442809 | 0.85 | MAPT (0.52) | WNT3AMAPTLMNATP53 | |
| SCHEMBL1443877 | 0.84 | DRD2 (0.46) | WNT3AMAPTLMNATP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596932-A | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors | BAYER SCHERING PHARMA AG | 2012-07-18 | — | — | CN | claimed |