Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918347 | 0.79 | RAB9A (0.63) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL4874678 | 0.78 | AURKA (0.60) | MAPTNPC1RAB9AKMT2ATP53 | |
| SCHEMBL647152 | 0.77 | ROCK1 (0.58) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL4872285 | 0.77 | KMT2A (0.53) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4875132 | 0.73 | RAB9A (0.49) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL9254344 | 0.72 | MAPT (0.76) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL15648041 | 0.72 | RAB9A (0.66) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL274966 | 0.72 | ALDH1A1 (1.00) | MAPTALDH1A1HPGDNPC1RAB9A | |
| Michler'S Ketone SCHEMBL36517 | 0.72 | ALDH1A1 (1.00) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL24627774 | 0.71 | MAPT (0.73) | MAPTALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102656141-A | Hematopoietic growth factor mimetic small molecule compounds and their uses | LIGAND PHARM INC | 2012-09-05 | — | — | CN | disclosed |