Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aldicarb SCHEMBL21327721 | 1.00 | TDP1 (0.90) | TDP1ALDH1A1TSHRHSD17B10 | |
| Aldicarb SCHEMBL2349170 | 0.95 | TDP1 (0.93) | TDP1ALDH1A1TSHRHSD17B10 | |
| Aldicarb SCHEMBL271980 | 0.95 | TDP1 (0.93) | TDP1ALDH1A1TSHRHSD17B10 | |
| Aldicarb SCHEMBL7864399 | 0.95 | TDP1 (1.00) | TDP1ALDH1A1TSHRHSD17B10 | |
| Aldicarb SCHEMBL9781 | 0.95 | TDP1 (1.00) | TDP1ALDH1A1TSHRHSD17B10 | |
| Aldicarb SCHEMBL7626286 | 0.95 | TDP1 (1.00) | TDP1ALDH1A1TSHRHSD17B10 | |
| Aldicarb SCHEMBL4061104 | 0.95 | TDP1 (1.00) | TDP1ALDH1A1TSHRHSD17B10 | |
| Aldicarb SCHEMBL7864397 | 0.95 | TDP1 (1.00) | TDP1ALDH1A1TSHRHSD17B10 | |
| Aldicarb SCHEMBL3901576 | 0.93 | TDP1 (0.90) | TDP1ALDH1A1TSHRHSD17B10 | |
| Aldicarb SCHEMBL9464151 | 0.93 | TDP1 (0.90) | TDP1ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240130374-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING ROOT LESION NEMATODES | NEWLEAF SYMBIOTICS, INC. | 2024-04-25 | — | — | US | disclosed |
| US-20240065264-A1 | COMPOUNDS AND COMPOSITIONS FOR NEMATODE TREATMENT | UNIV IOWA STATE RES FOUND INC (US) | 2024-02-29 | — | — | US | disclosed |
| US-11871753-B2 | Methods and compositions for controlling root lesion nematodes | NEWLEAF SYMBIOTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-11832613-B2 | Compounds and compositions for nematode treatment | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| WO-2022125520-A1 | INSECT CELL MEMBRANE MICROPARTICLES FOR DETOXIFICATION OF INSECT POLLINATORS | CORNELL UNIVERSITY (US) | 2022-06-16 | — | — | WO | disclosed |
| US-20210298295-A1 | COMPOUNDS AND COMPOSITIONS FOR NEMATODE TREATMENT | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2021-09-30 | — | — | US | disclosed |
| US-20200315181-A1 | Methods and Compositions for Controlling Root Lesion Nematodes | NEWLEAF SYMBIOTICS, INC. | 2020-10-08 | — | — | US | disclosed |
| US-10716307-B2 | Methods and compositions for controlling root knot nematodes | NEWLEAF SYMBIOTICS, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| US-10448645-B2 | Methods and compositions for controlling Root Lesion Nematodes | NEWLEAF SYMBIOTICS, INC. (US) | 2019-10-22 | — | — | US | disclosed |
| US-20190008159-A1 | Methods and Compositions for Controlling Root Knot Nematodes | NEWLEAF SYMBIOTICS, INC. | 2019-01-10 | — | — | US | disclosed |
| EP-0469357-A1 | 1-[pyri(mi)dyl-(2)]-5-hydroxypyrazole microbicides | BAYER AG (DE) | 1992-02-05 | — | — | EP | disclosed |
| US-5075294-A | Insecticides, miticides, nematocides | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-24 | — | — | US | disclosed |
| US-4954529-A | MITICIDES, INSECTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-04 | — | — | US | disclosed |
| EP-0249015-B1 | SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM, AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-27 | — | — | EP | disclosed |
| US-4855309-A | Pyridine derivatives, agents containing same, and the use thereof as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
| EP-0317881-A2 | Pyridyl- and pyrazinyl compounds, process for their preparation, composition containing them and their use as fungicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-31 | — | — | EP | disclosed |
| EP-0249015-A1 | Silane derivatives, process for their preparation, agents containing them, and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-16 | — | — | EP | disclosed |
| EP-0243790-A1 | N-phenyl(thio)ureas and their functional derivatives, processes for their production and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-04 | — | — | EP | disclosed |
| US-4675326-A | MONO AND BIS-PYRIDINIUM OXIMES FOR ORGANOPHOSPHOROUS AND CARB AMATE POISONING | STATE OF ISRAEL, PRIME MINISTERS OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH | 1987-06-23 | — | — | US | disclosed |
| US-4263318-A | INSECTICIDES | THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1981-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210298295-A1 | COMPOUNDS AND COMPOSITIONS FOR NEMATODE TREATMENT | HNMT, TUBB6, SGMS2 | TDP1 2678/4885ALDH1A1 2714/4885TSHR 4125/4885 |
| US-20240065264-A1 | COMPOUNDS AND COMPOSITIONS FOR NEMATODE TREATMENT | HNMT, TUBB6, SGMS2 | TDP1 2678/4885ALDH1A1 2714/4885TSHR 4125/4885 |
| US-11832613-B2 | Compounds and compositions for nematode treatment | HNMT, TUBB6, SGMS2 | TDP1 2678/4885ALDH1A1 2714/4885TSHR 4125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.