Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MGAM | O43451 | 2/20 | 0.52 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SI | P14410 | 2/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618157 | 0.85 | RPS6KA3 (0.84) | RPS6KA3MAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2494163 | 0.81 | RPS6KA3 (0.77) | RPS6KA3KMT2AMAPTMGAMAMY1A | |
| SCHEMBL16104116 | 0.81 | PTK2 (0.73) | ATMPTK2KMT2AMAPTMGAM | |
| SCHEMBL7261935 | 0.80 | RPS6KA3 (0.53) | RPS6KA3ATMPTK2KMT2AMAPT | |
| SCHEMBL22375107 | 0.79 | RPS6KA3 (1.00) | RPS6KA3KMT2AMAPTMGAMAMY1A | |
| SCHEMBL3342201 | 0.79 | RPS6KA3 (0.73) | RPS6KA3PTK2KMT2AMGAMAMY1A | |
| SCHEMBL2490946 | 0.79 | RPS6KA3 (0.73) | RPS6KA3KMT2AMAPTMGAMAMY1A | |
| SCHEMBL7813053 | 0.77 | RPS6KA3 (0.70) | RPS6KA3KMT2AMAPTMGAMAMY1A | |
| SCHEMBL2491190 | 0.75 | RPS6KA3 (0.68) | RPS6KA3PTK2KMT2AMAPTMGAM | |
| SCHEMBL31267895 | 0.75 | RPS6KA3 (0.68) | RPS6KA3PTK2KMT2AMAPTMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102688233-B | Benzotriazole Derivative is as the synthesis of RSK2 inhibitor and application | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-02-17 | — | — | CN | disclosed |
| CN-102688233-A | Synthesis of benzotriazol derivative as RSK2 inhibitor and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2012-09-26 | — | — | CN | disclosed |