Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3920011 | 0.92 | MEN1 (0.52) | THRATHRBMEN1KMT2APKM | |
| SCHEMBL3912255 | 0.84 | KMT2A (0.52) | THRATHRBMEN1KMT2APKM | |
| SCHEMBL3913459 | 0.81 | THRA (0.54) | THRATHRBMAPK1POLB | |
| SCHEMBL4099188 | 0.80 | KMT2A (0.49) | MEN1KMT2APKMNPC1RAB9A | |
| SCHEMBL4099186 | 0.79 | MEN1 (0.52) | MEN1KMT2APKMNPC1RAB9A | |
| SCHEMBL5858736 | 0.78 | THRB (0.52) | THRATHRB | |
| SCHEMBL28801013 | 0.77 | THRA (0.56) | THRATHRBMEN1KMT2AMAPK1 | |
| SCHEMBL3909957 | 0.76 | KMT2A (0.46) | THRATHRBMEN1KMT2APKM | |
| SCHEMBL3910714 | 0.76 | KMT2A (0.46) | THRATHRBMEN1KMT2APKM | |
| SCHEMBL3914991 | 0.76 | MAPT (0.52) | MEN1KMT2APKMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102718718-B | Preparation method for 3,5-dibromo-4-(5-benzimidazole oxygen group)phenylacetic acid | UNIV SHAOXING | 2014-09-24 | — | — | CN | disclosed |
| CN-102718718-A | Preparation method for 3,5-dibromo-4-(5-benzimidazole oxygen group)phenylacetic acid | UNIV SHAOXING | 2012-10-10 | — | — | CN | disclosed |