Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 13/20 | 0.56 |
| ▸ | THRB | P10828 | 13/20 | 0.56 |
| ▸ | PCNA | P12004 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3136070 | 0.86 | THRA (0.45) | THRATHRBMEN1KMT2APOLB | |
| SCHEMBL3913459 | 0.84 | THRA (0.54) | THRATHRBPCNAESR1NR3C1 | |
| SCHEMBL27890955 | 0.82 | FFAR1 (0.66) | MEN1KMT2AFFAR1POLBMAPK1 | |
| SCHEMBL5073534 | 0.81 | THRA (0.60) | THRATHRBPCNAESR1NR3C1 | |
| SCHEMBL5859480 | 0.81 | THRA (0.64) | THRATHRBPCNAESR1NR3C1 | |
| SCHEMBL3911244 | 0.81 | MEN1 (0.48) | THRATHRBMEN1KMT2APOLB | |
| SCHEMBL3133551 | 0.80 | MEN1 (0.68) | THRATHRBMEN1KMT2AFFAR1 | |
| SCHEMBL3137474 | 0.78 | MEN1 (0.49) | MEN1KMT2APOLBMAPK1KDM4E | |
| SCHEMBL5381954 | 0.77 | HSPB1 (0.51) | MEN1KMT2APOLBMAPK1KDM4E | |
| SCHEMBL27890925 | 0.77 | THRA (0.51) | THRATHRBMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102718718-B | Preparation method for 3,5-dibromo-4-(5-benzimidazole oxygen group)phenylacetic acid | UNIV SHAOXING | 2014-09-24 | — | — | CN | disclosed |
| CN-102718718-A | Preparation method for 3,5-dibromo-4-(5-benzimidazole oxygen group)phenylacetic acid | UNIV SHAOXING | 2012-10-10 | — | — | CN | disclosed |