Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426981 | 0.83 | KMT2A (0.54) | EPHX2TDP1ALDH1A1ALDH3A1ALDH2 | |
| SCHEMBL9389160 | 0.82 | ALDH1A1 (0.51) | TDP1ALDH1A1ALDH3A1CHRM1L3MBTL1 | |
| SCHEMBL20622393 | 0.80 | L3MBTL1 (0.58) | EPHX2ALDH1A1ALDH3A1ALDH2CHRM1 | |
| SCHEMBL11458214 | 0.80 | NR3C1 (0.53) | EPHX2TDP1ALDH1A1ALDH3A1ALDH2 | |
| SCHEMBL18176034 | 0.79 | NR3C1 (0.58) | EPHX2ALDH1A1ALDH3A1ALDH2CHRM1 | |
| SCHEMBL9253600 | 0.79 | EPHX2 (0.47) | EPHX2TDP1ALDH1A1ALDH3A1ALDH2 | |
| SCHEMBL6360254 | 0.78 | NOTUM (0.53) | ALDH1A1ALDH3A1ALDH2CES1NOTUM | |
| SCHEMBL28680953 | 0.74 | NOTUM (0.49) | TDP1ALDH1A1ALDH3A1CES1CACNA1G | |
| SCHEMBL5474552 | 0.73 | PARP1 (0.49) | EPHX2TDP1ALDH1A1ALDH3A1ALDH2 | |
| SCHEMBL1488276 | 0.72 | L3MBTL1 (0.56) | EPHX2L3MBTL1DDB1CRBNKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102892766-A | Kinase inhibitors and method of treating cancer with same | UNIV HEALTH NETWORK | 2013-01-23 | — | — | CN | disclosed |