Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31402850 | 0.80 | UTS2R (0.44) | ALKBH5FTOGPR3UTS2RGABRP | |
| SCHEMBL27908745 | 0.79 | PGR (0.49) | UTS2RKDM4EALDH1A1LMNAGAA | |
| SCHEMBL3333888 | 0.78 | DYRK1A (0.59) | ALKBH5FTOGPR3GABRPGABRD | |
| SCHEMBL27908740 | 0.77 | ALDH1A1 (0.41) | UTS2RKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL27891760 | 0.77 | MCL1 (0.60) | UTS2RKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL3340225 | 0.77 | ALKBH5 (0.51) | ALKBH5FTOGPR3GABRPGABRD | |
| SCHEMBL16596110 | 0.77 | ALKBH5 (0.51) | ALKBH5FTOGPR3GABRPGABRD | |
| SCHEMBL27992450 | 0.77 | ALKBH5 (0.51) | ALKBH5FTOGPR3UTS2RGABRP | |
| SCHEMBL3339645 | 0.77 | ALKBH5 (0.51) | ALKBH5FTOGPR3GABRPGABRD | |
| SCHEMBL27891742 | 0.76 | MCL1 (0.54) | UTS2RALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146080-B | Beta-carboline alkali derivative compounds and application thereof | XINJIANG HUASHIDAN PHARMACEUTICAL CO LTD | 2013-01-30 | — | — | CN | disclosed |