Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896622 | 0.91 | CNR2 (0.35) | CNR2RENCYP3A4 | |
| SCHEMBL2814040 | 0.89 | CNR2 (0.34) | CNR2RENALDH1A1TSHRKMT2A | |
| SCHEMBL2814043 | 0.89 | CNR2 (0.34) | CNR2RENALDH1A1TSHRKMT2A | |
| SCHEMBL2791612 | 0.89 | PROKR1 (0.39) | CNR2FPR2ALDH1A1TSHRKMT2A | |
| SCHEMBL2817635 | 0.89 | PROKR1 (0.39) | CNR2FPR2ALDH1A1TSHRKMT2A | |
| SCHEMBL7891178 | 0.85 | CNR2 (0.36) | CNR2RENCYP3A4 | |
| SCHEMBL2791623 | 0.85 | FPR2 (0.34) | CNR2FPR2RENALDH1A1TSHR | |
| SCHEMBL2789222 | 0.84 | PROKR1 (0.41) | CNR2FPR2RENALDH1A1TSHR | |
| SCHEMBL2789818 | 0.82 | CNR2 (0.35) | CNR2FPR2ALDH1A1TSHRKMT2A | |
| SCHEMBL739919 | 0.81 | HRH1 (0.45) | CYP3A4KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |