Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 7/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2814043 | 1.00 | CNR2 (0.34) | CNR2RENALDH1A1TSHRKMT2A | |
| SCHEMBL7898296 | 0.92 | CNR2 (0.33) | CNR2RENCYP3A4 | |
| SCHEMBL2790483 | 0.91 | ALDH1A1 (0.31) | RENALDH1A1TSHRKMT2A | |
| SCHEMBL2790479 | 0.91 | ALDH1A1 (0.31) | RENALDH1A1TSHRKMT2A | |
| SCHEMBL2790813 | 0.90 | PROKR1 (0.36) | CNR2ALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL2789237 | 0.89 | CNR2 (0.37) | CNR2RENALDH1A1TSHRKMT2A | |
| SCHEMBL2789916 | 0.87 | REN (0.32) | RENALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL7902463 | 0.83 | USP30 (0.33) | — | |
| SCHEMBL7902090 | 0.83 | USP30 (0.32) | RENCYP3A4 | |
| SCHEMBL7897738 | 0.82 | PADI4 (0.37) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |