Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771320 | 0.88 | PTGES (0.54) | PTGESMEN1ALDH1A1GAAKMT2A | |
| SCHEMBL2789297 | 0.88 | PDE4A (0.47) | ELANEDHODHPDE4APDE4BPDE4C | |
| SCHEMBL2787046 | 0.88 | PTGES (0.40) | PTGESPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2787871 | 0.86 | PDE4D (0.40) | PTGESPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2791143 | 0.84 | DHODH (0.42) | ELANEDHODHPDE4APDE4BPDE4C | |
| SCHEMBL2789925 | 0.82 | PDE4A (0.52) | PTGESPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2788405 | 0.82 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2771225 | 0.82 | PTGES (0.54) | PTGESMEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL2772806 | 0.81 | KDM4E (0.48) | PTGESPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2805298 | 0.81 | PDE4A (0.55) | PTGESELANEDHODHPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |