Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 8/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792440 | 0.89 | CNR2 (0.36) | CNR2CFDDPP4DPP7 | |
| SCHEMBL2791998 | 0.88 | CNR2 (0.35) | CNR2CFDDPP4DPP7 | |
| SCHEMBL2790195 | 0.87 | AKT1 (0.35) | CNR2CFDDPP4 | |
| SCHEMBL2791483 | 0.85 | CNR2 (0.33) | CNR2CFDDPP4DPP7 | |
| SCHEMBL2817352 | 0.82 | PROKR1 (0.45) | CNR2CFD | |
| SCHEMBL2789449 | 0.82 | CFD (0.35) | CNR2CFDCYP3A4DPP4DPP7 | |
| SCHEMBL2789519 | 0.82 | CNR2 (0.36) | CNR2CFDDPP4DPP7 | |
| SCHEMBL7898489 | 0.81 | DPP4 (0.38) | CNR2CFDDPP4 | |
| SCHEMBL2791310 | 0.81 | CNR2 (0.36) | CNR2CFDCYP3A4DPP4 | |
| SCHEMBL2812030 | 0.81 | CNR2 (0.36) | CNR2CFDDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |