Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 9/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792686 | 0.89 | DPP4 (0.34) | CFDDPP4DPP7CYP1A2CYP3A4 | |
| SCHEMBL2789823 | 0.85 | CNR2 (0.31) | CNR2 | |
| SCHEMBL2789341 | 0.82 | CNR2 (0.37) | CFDCNR2DPP4DPP7CYP3A4 | |
| SCHEMBL2792440 | 0.82 | CNR2 (0.36) | CFDCNR2DPP4DPP7DPP8 | |
| SCHEMBL2791998 | 0.81 | CNR2 (0.35) | CFDCNR2DPP4DPP7DPP8 | |
| SCHEMBL2790195 | 0.79 | AKT1 (0.35) | CFDCNR2DPP4PADI4 | |
| SCHEMBL2791483 | 0.79 | CNR2 (0.33) | CFDCNR2DPP4DPP7 | |
| SCHEMBL2791066 | 0.78 | PROKR1 (0.39) | DPP4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2789378 | 0.76 | PIK3CA (0.33) | DPP4DPP7CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2792058 | 0.76 | CNR2 (0.48) | CNR2CYP3A4PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |