Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 11/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792440 | 0.92 | CNR2 (0.36) | CNR2CFDDPP4ALDH1A1TSHR | |
| SCHEMBL740825 | 0.88 | CFD (0.36) | CFDDPP4ALDH1A1TSHRKMT2A | |
| SCHEMBL740824 | 0.88 | CFD (0.36) | CFDDPP4ALDH1A1TSHRKMT2A | |
| SCHEMBL2789341 | 0.88 | CNR2 (0.37) | CNR2CFDDPP4DPP7 | |
| SCHEMBL7898298 | 0.87 | WNT3A (0.32) | CNR2PDE2APDE3AMAPK1 | |
| SCHEMBL2790195 | 0.86 | AKT1 (0.35) | CNR2CFDDPP4 | |
| SCHEMBL2789519 | 0.85 | CNR2 (0.36) | CNR2CFDDPP4PDE2APDE3A | |
| SCHEMBL2791483 | 0.84 | CNR2 (0.33) | CNR2CFDDPP4PDE3ADPP7 | |
| SCHEMBL2791310 | 0.84 | CNR2 (0.36) | CNR2CFDDPP4PDE2APDE3A | |
| SCHEMBL741237 | 0.84 | KCNH2 (0.42) | PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | claimed |
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |