Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6845118 | 1.00 | CHRNA7 (0.55) | CHRNA7UHRF1CHRNB2CHRNB4CHRNA4 | |
| Hydrochloric Acid SCHEMBL12983296 | 0.98 | CHRNA7 (0.54) | CHRNA7UHRF1CHRNB2CHRNB4CHRNA4 | |
| Hydrochloric Acid SCHEMBL12983298 | 0.98 | CHRNA7 (0.54) | CHRNA7UHRF1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL10238795 | 0.79 | CHRNA7 (0.57) | CHRNA7UHRF1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL6845140 | 0.79 | CHRNA7 (0.57) | CHRNA7UHRF1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL18818329 | 0.79 | NOS3 (0.47) | CHRNA7CHRNB2CHRNB4CHRNA4CHRNA2 | |
| SCHEMBL29649333 | 0.78 | CHRNA7 (0.55) | CHRNA7UHRF1CHRNB2CHRNB4CHRNA4 | |
| Hydrochloric Acid SCHEMBL18794989 | 0.78 | NOS3 (0.46) | CHRNA7CHRNB2CHRNB4CHRNA4CHRNA2 | |
| SCHEMBL23977210 | 0.74 | CYP11B1 (0.38) | CHRNA7CYP11B1CYP11B2 | |
| SCHEMBL31040816 | 0.74 | CYP11B1 (0.38) | CHRNA7CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762560-A | Disubstituted heteroaryl-fused pyridines | NOVARTIS AG | 2012-10-31 | — | — | CN | disclosed |