Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD1 | P21728 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29792600 | 0.85 | CHRNA7 (0.44) | CHRNA7GFRA3RETUGT2B17PGR | |
| SCHEMBL23088396 | 0.85 | CHRNA7 (0.44) | CHRNA7GFRA3RETUGT2B17PGR | |
| SCHEMBL6845140 | 0.79 | CHRNA7 (0.57) | CHRNA7HCRTR1HCRTR2CHRNB2CHRNB4 | |
| SCHEMBL10238795 | 0.79 | CHRNA7 (0.57) | CHRNA7HCRTR1HCRTR2CHRNB2CHRNB4 | |
| SCHEMBL18094367 | 0.78 | GFRA3 (0.43) | CHRNA7GFRA3RETPGRCHRNB2 | |
| SCHEMBL27894710 | 0.78 | CHRNA7 (0.55) | CHRNA7HCRTR1HCRTR2CHRNB2CHRNB4 | |
| SCHEMBL26307220 | 0.78 | GFRA3 (0.43) | CHRNA7GFRA3RETPGRCHRNB2 | |
| SCHEMBL16800643 | 0.78 | GFRA3 (0.43) | CHRNA7GFRA3RETPGRCHRNB2 | |
| SCHEMBL6845118 | 0.78 | CHRNA7 (0.55) | CHRNA7HCRTR1HCRTR2CHRNB2CHRNB4 | |
| SCHEMBL15464723 | 0.77 | CHRNB2 (0.57) | CHRNA7GFRA3RETUGT2B17PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306635-A1 | TDO2 Inhibitors | GENENTECH, INC. | 2022-09-29 | — | — | US | disclosed |
| CN-110072864-B | TDO2 inhibitors | 基因泰克公司 | 2022-05-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306635-A1 | TDO2 Inhibitors | TDO2, IDO2, IDO1 | CHRNA7 3586/4885GFRA3 4462/4885RET 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.