Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380223 | 0.80 | SMN1; SMN2 (0.42) | GAAKDM4EHPGDHSD17B10POLB | |
| SCHEMBL9117601 | 0.75 | F11 (0.46) | GAAKDM4EHPGDHSD17B10POLB | |
| SCHEMBL9241452 | 0.72 | PTPN1 (0.52) | GAAKDM4EHPGDHSD17B10POLB | |
| SCHEMBL20983221 | 0.71 | POLB (0.52) | GAAKDM4EHPGDHSD17B10POLB | |
| SCHEMBL4928410 | 0.71 | GPR17 (0.43) | GAAKDM4EHPGDHSD17B10POLB | |
| SCHEMBL7128691 | 0.70 | GAA (0.61) | GAAKDM4EHPGDHSD17B10POLB | |
| SCHEMBL10759270 | 0.70 | GAA (0.39) | GAAKDM4EHPGDHSD17B10POLB | |
| SCHEMBL9235372 | 0.70 | CA2 (0.42) | GAAKDM4EHPGDHSD17B10HIF1A | |
| SCHEMBL9658959 | 0.70 | AKR1B1 (0.46) | HSD17B10TSHRTDP1AKR1B1CSNK2A2 | |
| SCHEMBL31310136 | 0.70 | GPR17 (0.39) | GAAKDM4EHPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524966-B2 | Method for preparing ladderanes | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-04-28 | — | — | US | claimed |
| US-20090088572-A1 | METHOD FOR PREPARING LADDERANES | NATIONAL SCIENCE FOUNDATION | 2009-04-02 | — | — | US | claimed |
| WO-2007089785-A2 | APPARATUS AND SEMICONDUCTOR CO-CRYSTAL | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-08-09 | — | — | WO | claimed |
| WO-2005035473-A2 | METHOD FOR PREPARING LADDERANES FROM PRE-ORIENTED POLYENES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2005-04-21 | — | — | WO | claimed |
| US-8328933-B2 | Apparatus and semiconductor co-crystal | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2012-12-11 | — | — | US | disclosed |
| US-20100148154-A1 | APPARATUS AND SEMICONDUCTOR CO-CRYSTAL | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2010-06-17 | — | — | US | disclosed |
| US-7524966-B2 | Method for preparing ladderanes | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-04-28 | — | — | US | disclosed |
| US-7524373-B2 | Apparatus and semiconductor co-crystal | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-04-28 | — | — | US | disclosed |
| US-20090088572-A1 | METHOD FOR PREPARING LADDERANES | NATIONAL SCIENCE FOUNDATION | 2009-04-02 | — | — | US | disclosed |
| WO-2007089785-A2 | APPARATUS AND SEMICONDUCTOR CO-CRYSTAL | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-08-09 | — | — | WO | disclosed |
| US-20070178621-A1 | Apparatus and semiconductor co-crystal | UNIVERISTY OF IOWA RESEARCH FOUNDATION | 2007-08-02 | — | — | US | disclosed |
| WO-2005035473-A2 | METHOD FOR PREPARING LADDERANES FROM PRE-ORIENTED POLYENES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2005-04-21 | — | — | WO | disclosed |