Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA4 | P22748 | 4/20 | 0.42 |
| ▸ | CA6 | P23280 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11803971 | 0.73 | AKR1B1 (0.44) | CA2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL9117601 | 0.73 | F11 (0.46) | CA2CA1CA4CA6PTPN1 | |
| SCHEMBL30940421 | 0.71 | AKR1B1 (0.42) | CA2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL9476644 | 0.70 | TTR (0.38) | CA2CA1CA4CA6PTPN1 | |
| SCHEMBL2789591 | 0.70 | GAA (0.42) | CA2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL9241452 | 0.66 | PTPN1 (0.52) | CA2CA1CA4CA6PTPN1 | |
| SCHEMBL48572 | 0.66 | ALDH1A1 (0.90) | CA2CA1CA4CA6PTPN1 | |
| SCHEMBL4697289 | 0.62 | AKR1B1 (0.36) | CA2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| Pentabromophenol SCHEMBL268325 | 0.62 | ALOX15 (1.00) | CA2CA1CA4CA6PTPN1 | |
| SCHEMBL8642649 | 0.62 | CA1 (0.82) | CA2CA1CA4CA6PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025712-A1 | HOMOGENTISIC ACID DERIVATIVES, METHODS OF TREATMENT OF DISEASE STATES MEDIATED BY PROTEIN KINASE C USING HOMOGENTISIC ACID DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-28 | — | — | WO | disclosed |