Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186168 | 0.84 | HCAR2 (0.52) | HCAR2KDM4EHDAC4SMN1; SMN2PKM | |
| SCHEMBL27709390 | 0.80 | ALDH1A1 (0.33) | HCAR2LMNAALDH1A1HPGDF2 | |
| SCHEMBL28112074 | 0.79 | HCAR2 (0.43) | HCAR2LMNASMN1; SMN2NPC1TP53 | |
| SCHEMBL27618613 | 0.78 | SMN1; SMN2 (0.42) | LMNAALDH1A1HPGDF2GLA | |
| SCHEMBL27709330 | 0.78 | L3MBTL1 (0.40) | LMNAALDH1A1CYP3A4KDM4EALOX12 | |
| SCHEMBL27736514 | 0.75 | KMT2A (0.48) | HCAR2LMNAALDH1A1F2KDM4E | |
| SCHEMBL23829538 | 0.74 | HCAR2 (0.39) | HCAR2LMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28268872 | 0.73 | NPC1 (0.32) | ALDH1A1CYP3A4SMN1; SMN2MEN1NPC1 | |
| SCHEMBL27896166 | 0.72 | HCAR2 (0.37) | HCAR2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3506762 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330000-A | 3-carbonylamino-5-cyclopentyl-1 FI-pyrrole compound having inhibitory activity against CDK2 | 辉瑞公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-107412232-B | A kind of children use C20H18N6Na2O7S4Pharmaceutical entities composition and preparation | 广东金城金素制药有限公司 | 2019-12-03 | — | — | CN | disclosed |
| CN-108559979-A | A kind of chemical nickel-plating liquid and preparation method thereof | 永星化工(上海)有限公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-108165959-A | Chemical bronze plating liquid | 永星化工(上海)有限公司 | 2018-06-15 | — | — | CN | disclosed |
| CN-108103540-A | Tin alloy electric plating liquid | 永星化工(上海)有限公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-107857740-A | The synthetic method of the thiazolyl acetic acid of 2 sulfydryl of Cefodizime Sodium intermediate, 4 methyl 5 | 山东金城医药化工有限公司 | 2018-03-30 | — | — | CN | disclosed |
| CN-107412232-A | A kind of children use C20H18N6Na2O7S4Pharmaceutical entities composition and preparation | 广东金城金素制药有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-102911134-A | Synthesis process for cefditoren pivoxil intermediate | ZHENG BOWEN | 2013-02-06 | — | — | CN | disclosed |
| CN-102452997-A | Synthesis process of cefditoren pivoxil intermediate | HAO WANG | 2012-05-16 | — | — | CN | disclosed |
| WO-2010065322-A1 | CONCURRENT IDENTIFICATION OF MULTITUDES OF POLYPEPTIDES | RESEARCH TRIANGLE INSTITUTE (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20030138831-A1 | Method for sequencing and characterizing polymeric biomolecules using aptamers and a method for producing aptamers | PRAELUX INCORPORATED (US) | 2003-07-24 | — | — | US | disclosed |
| US-6515120-B1 | DNA/RNA sequences; structural characterization; aptamers thatrecognize and bind to specific nucleotides | PRAELUX INCORPORATED | 2003-02-04 | — | — | US | disclosed |
| WO-2000071755-A2 | METHOD FOR SEQUENCY AND CHARACTERIZING POLYMERIC BIOMOLECULES USING APTAMERS AND A METHOD FOR PRODUCING APTAMERS | PRAELUX INCORPORATED (US) | 2000-11-30 | — | — | WO | disclosed |
| WO-1994002844-A1 | THIOBENZOYLATION METHOD OF PEPTIDE SEQUENCING WITH GAS CHROMATOGRAPHY AND MASS SPECTROMETRIC DETECTION | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1994-02-03 | — | — | WO | disclosed |
| US-5246865-A | Thiobenzoylation method of peptide sequencing with gas chromatography and mass spectrometric detection | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1993-09-21 | — | — | US | disclosed |