Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237343 | 0.74 | ALDH1A1 (0.46) | CYP3A4RECQLCYP1A2PPARGPPARA | |
| SCHEMBL28384602 | 0.69 | MEN1 (0.47) | MEN1KMT2AL3MBTL1HTTNPC1 | |
| SCHEMBL28388205 | 0.67 | L3MBTL1 (0.44) | MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL27634846 | 0.64 | KMT2A (0.50) | MEN1KMT2AL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL28385517 | 0.64 | MEN1 (0.47) | MEN1KMT2AL3MBTL1HTTNPC1 | |
| SCHEMBL28771530 | 0.63 | CYP3A4 (0.43) | CYP3A4RECQLCYP1A2PPARGPPARA | |
| SCHEMBL28771528 | 0.63 | CYP3A4 (0.43) | CYP3A4RECQLCYP1A2PPARGPPARA | |
| SCHEMBL2212129 | 0.63 | CYP3A4 (0.43) | MEN1KMT2AL3MBTL1HTTCYP3A4 | |
| SCHEMBL5940486 | 0.63 | SMN1; SMN2 (0.55) | CYP3A4RECQLCYP1A2PPARGPPARA | |
| SCHEMBL5556046 | 0.62 | CYP3A4 (0.49) | CYP3A4RECQLCYP1A2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762101-A | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | HIGH POINT PHARMACEUTICALS LLC | 2012-10-31 | — | — | CN | disclosed |