Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054871 | 0.82 | PIK3CD (0.39) | TSHRSMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL28054733 | 0.75 | — | — | |
| SCHEMBL27896515 | 0.73 | HSD17B10 (0.50) | TSHRHSD17B10LMNAALOX15SMN1; SMN2 | |
| SCHEMBL27896421 | 0.72 | KMT2A (0.42) | TSHRLMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL27896395 | 0.71 | LMNA (0.41) | TSHRLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL27896413 | 0.71 | CYP1A2 (0.39) | — | |
| SCHEMBL27896436 | 0.71 | LOXL2 (0.34) | POLB | |
| SCHEMBL27879617 | 0.71 | NR1H2 (0.30) | — | |
| SCHEMBL27896387 | 0.70 | TSHR (0.40) | TSHRSMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL3891473 | 0.67 | HSD17B10 (0.75) | TSHRHSD17B10LMNAALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |