Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896416 | 0.80 | MEN1 (0.46) | HSD17B10POLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27879607 | 0.79 | ADAM17 (0.41) | POLBALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL27896381 | 0.78 | ACHE (0.38) | HSD17B10GAAPOLBTSHRALDH1A1 | |
| SCHEMBL28159525 | 0.76 | GAA (0.57) | HSD17B10GAAPOLBAPOBEC3AAPOBEC3G | |
| SCHEMBL13753536 | 0.76 | TSHR (0.68) | HSD17B10GAAPOLBAPOBEC3AAPOBEC3G | |
| SCHEMBL28846715 | 0.76 | GAA (0.57) | HSD17B10GAAPOLBAPOBEC3AAPOBEC3G | |
| SCHEMBL27879665 | 0.75 | CHRNA7 (0.51) | POLBALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL27896385 | 0.75 | TSHR (0.48) | TSHRALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL6290035 | 0.74 | ALDH1A1 (0.60) | HSD17B10GAAPOLBAPOBEC3AAPOBEC3G | |
| SCHEMBL6290034 | 0.74 | ALDH1A1 (0.60) | HSD17B10GAAPOLBAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |