Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896392 | 0.85 | GFER (0.50) | ALDH1A1MEN1KMT2AHSD11B1TSHR | |
| SCHEMBL13753517 | 0.78 | HPGD (0.71) | HPGDALDH1A1SMN1; SMN2GAAKDM4E | |
| SCHEMBL27896409 | 0.78 | HTT (0.51) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL18767537 | 0.77 | ALDH1A1 (0.57) | HPGDALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL4001869 | 0.76 | ALDH1A1 (0.74) | HPGDALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL13803530 | 0.76 | ALDH1A1 (0.59) | HPGDALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL4001868 | 0.76 | ALDH1A1 (0.74) | HPGDALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL27011217 | 0.76 | ALDH1A1 (0.74) | HPGDALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL27896574 | 0.75 | CHRNB2 (0.40) | HPGDALDH1A1EPHX2GAAMEN1 | |
| SCHEMBL28054724 | 0.75 | DPP4 (0.43) | HPGDEPHX2GAAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |