Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | RHOC | P08134 | 1/20 | 0.34 |
| ▸ | RHOA | P61586 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896385 | 0.76 | TSHR (0.48) | HSD11B1EPHX2KMT2A | |
| SCHEMBL27896574 | 0.76 | CHRNB2 (0.40) | POLBEPHX2GAAHPGDKMT2A | |
| SCHEMBL27896410 | 0.75 | HPGD (0.50) | POLBHSD11B1EPHX2GAAHPGD | |
| SCHEMBL27879658 | 0.74 | PREP (0.49) | DPP4DPP8POLBGRM5EPHX2 | |
| SCHEMBL27896392 | 0.74 | GFER (0.50) | HSD11B1GRM5GFERKMT2A | |
| SCHEMBL27879605 | 0.73 | SCN9A (0.41) | DPP4HSD11B1GRM5HPGDKMT2A | |
| SCHEMBL27879612 | 0.72 | SMN1; SMN2 (0.57) | POLBHSD11B1HPGD | |
| SCHEMBL27896515 | 0.71 | HSD17B10 (0.50) | POLBGAAHPGDKMT2A | |
| SCHEMBL30009432 | 0.71 | HPGD (0.69) | POLBHSD11B1GAAHPGDKMT2A | |
| SCHEMBL7408815 | 0.71 | POLB (0.36) | DPP4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |