Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896385 | 0.81 | TSHR (0.48) | HTTKMT2AMEN1TSHRCYP2C9 | |
| SCHEMBL27879623 | 0.80 | KMT2A (0.48) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL17502621 | 0.79 | KMT2A (0.68) | HTTHSP90AA1HSP90AB1KMT2AMEN1 | |
| SCHEMBL17502708 | 0.78 | HTT (0.57) | HTTHSP90AA1HSP90AB1KMT2AMEN1 | |
| SCHEMBL27896407 | 0.78 | HSD11B1 (0.57) | CYP2C9POLBHSD11B1ALDH1A1 | |
| SCHEMBL27896410 | 0.78 | HPGD (0.50) | KMT2AMEN1TSHRCYP2C9CYP2C19 | |
| SCHEMBL27896422 | 0.77 | TDP1 (0.42) | KMT2AMEN1CYP2C9CYP2C19POLB | |
| SCHEMBL15743803 | 0.77 | HTT (0.56) | HTTHSP90AA1HSP90AB1KMT2AMEN1 | |
| SCHEMBL28054630 | 0.77 | HSD17B10 (0.41) | HSP90AA1HSP90AB1LMNANPSR1 | |
| SCHEMBL27896392 | 0.76 | GFER (0.50) | KMT2AMEN1TSHRPREPHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |