Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 6/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833632 | 0.83 | MCL1 (0.50) | MCL1MEN1NPC1GAARAB9A | |
| SCHEMBL28229955 | 0.72 | SLC9A1 (0.48) | SLC9A1FABP4F10PLA2G10F2 | |
| SCHEMBL29631921 | 0.71 | CHRM2 (0.41) | SLC9A1F10PLA2G10 | |
| SCHEMBL2133036 | 0.71 | CHRM2 (0.41) | SLC9A1F10PLA2G10 | |
| SCHEMBL2276306 | 0.70 | SLC9A1 (0.64) | SLC9A1F10PLA2G10MCL1GAA | |
| SCHEMBL8260 | 0.70 | DAO (0.59) | SLC9A1FABP4F10PLA2G10MCL1 | |
| SCHEMBL12570686 | 0.70 | GABRG2 (0.43) | SLC9A1F10PLA2G10CA12CA9 | |
| SCHEMBL8551062 | 0.70 | MCL1 (0.57) | MCL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL29020785 | 0.69 | BRD9 (0.38) | MEN1NPC1RAB9AKMT2ALCK | |
| SCHEMBL28721455 | 0.69 | ALDH1A1 (0.45) | PLA2G10MCL1KMT2ALCKBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781914-A | Indole derivatives | TAKEDA PHARMACEUTICAL | 2012-11-14 | — | — | CN | disclosed |