Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28016467 | 0.88 | SCN5A (0.41) | SCN5ASCN9ACHRM3KIF11CCR2 | |
| SCHEMBL27898493 | 0.87 | SCN5A (0.37) | SCN5ASCN9ACHRM3KIF11HTR2A | |
| SCHEMBL28801846 | 0.87 | SCN5A (0.41) | SCN5ASCN9ACHRM3KIF11HTR2A | |
| SCHEMBL27916156 | 0.86 | OPRK1 (0.39) | CHRM3KIF11HTR2AHTR2CADRA1A | |
| SCHEMBL27898451 | 0.86 | RIPK1 (0.32) | KIF11RIPK1 | |
| SCHEMBL27898448 | 0.86 | KCNN4 (0.36) | CHRM3KIF11CCR2OPRM1RIPK1 | |
| SCHEMBL27916130 | 0.84 | CRHR1 (0.40) | — | |
| SCHEMBL28016464 | 0.84 | ALDH1A1 (0.39) | KIF11HTR2AHTR2CADRA1AOPRK1 | |
| SCHEMBL27898530 | 0.82 | HTR2A (0.43) | HTR2AHTR2CADRA1AOPRK1KCNH2 | |
| SCHEMBL27898458 | 0.79 | NPC1 (0.39) | CCR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012207-B | Diaryl propionyl-N-methyl hydroxamic acid type urease inhibitor and synthesis and application thereof | UNIV JISHOU | 2015-05-27 | — | — | CN | disclosed |
| CN-103012207-A | Diaryl propionyl-N-methyl hydroxamic acid type urease inhibitor and synthesis and application thereof | UNIV JISHOU | 2013-04-03 | — | — | CN | disclosed |