Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 6/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | ME2 | P23368 | 1/20 | 0.34 |
| ▸ | ME1 | P48163 | 1/20 | 0.34 |
| ▸ | ME3 | Q16798 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562645 | 0.76 | HDAC6 (0.41) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL2560721 | 0.75 | VNN1 (0.47) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL2566143 | 0.74 | VNN1 (0.49) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL19942194 | 0.73 | VNN1 (0.39) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL2560278 | 0.72 | HDAC3 (0.53) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL17080669 | 0.70 | HDAC6 (0.39) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL12288597 | 0.69 | VNN1 (0.44) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22975115 | 0.68 | KMT2A (0.46) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL2560412 | 0.68 | GPR55 (0.45) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL18466466 | 0.68 | HDAC3 (0.48) | VNN1HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105712974-A | Certain Amino-Pyridazines, Compositions Thereof, And Methods Of Their Use | 赛特凯恩蒂克公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-103025331-B | Certain amino-pyrimidines, compositions thereof and methods of use thereof | CYTOKINETICS, INC. (US) | 2016-03-02 | — | — | CN | disclosed |
| CN-103025331-A | Certain amino-pyrimidines, compositions thereof and methods of use thereof | CYTOKINETICS INC | 2013-04-03 | — | — | CN | disclosed |