⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminothiazole SCHEMBL6051173 | 0.94 | ALDH1A1 (0.88) | — | |
| Aminothiazole SCHEMBL1136755 | 0.94 | — | — | |
| Aminothiazole SCHEMBL7401 | 0.94 | — | — | |
| Aminothiazole SCHEMBL4962431 | 0.94 | ALDH1A1 (1.00) | — | |
| Aminothiazole SCHEMBL10428703 | 0.94 | — | — | |
| Aminothiazole SCHEMBL27943753 | 0.92 | — | — | |
| Aminothiazole SCHEMBL1641818 | 0.91 | — | — | |
| Aminothiazole SCHEMBL5781624 | 0.91 | — | — | |
| Aminothiazole SCHEMBL2350289 | 0.91 | — | — | |
| Aminothiazole SCHEMBL11884793 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101263131-B | Urea glucokinase activators | TRANSTECH PHARMA INC | 2013-04-24 | — | — | CN | disclosed |