Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18686342 | 0.81 | MGLL (0.61) | TACR1ALDH1A1L3MBTL1MC4R | |
| SCHEMBL7799838 | 0.74 | LIMK2 (0.55) | TACR1MEN1KMT2APOLBMC4R | |
| SCHEMBL4679488 | 0.72 | MC4R (0.43) | TACR1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL5106701 | 0.72 | MEN1 (0.43) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL4959434 | 0.71 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4529470 | 0.70 | MC4R (0.57) | MEN1KMT2AHTTMC4R | |
| SCHEMBL19520529 | 0.69 | PDK2 (0.66) | MEN1KMT2AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL14834137 | 0.69 | MGLL (0.65) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1581379 | 0.69 | FAAH (0.60) | SMN1; SMN2 | |
| SCHEMBL15536848 | 0.69 | MAPT (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |