Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14834137 | 0.85 | MGLL (0.65) | MGLLKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL3660279 | 0.83 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL14834225 | 0.81 | MGLL (0.79) | MGLLKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL27917924 | 0.81 | ALDH1A1 (0.70) | KMT2AMEN1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL27917785 | 0.80 | ALDH1A1 (0.54) | MGLLKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL18446034 | 0.80 | HTR1A (0.54) | MGLLKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL27917796 | 0.80 | ALDH1A1 (0.68) | MGLLKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL27900139 | 0.80 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL3987599 | 0.79 | GRIN2B (0.46) | CYP2C9 | |
| SCHEMBL27900131 | 0.79 | FBP1 (0.57) | MGLLALDH1A1PKMSMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |