SCHEMBL27900779

SCHEMBL27900779

CC(O)C(c1ccccc1Cl)C(C)COC(N)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.43
CYP1A2 P05177 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CYP2D6 P10635 2/20 0.42
PKM P14618 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
ADRB2 P07550 4/20 0.40
ADRB1 P08588 4/20 0.40
ADRB3 P13945 2/20 0.40
AOC3 Q16853 1/20 0.39
CXCL8 P10145 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
AVPR2 P30518 1/20 0.35
AVPR1A P37288 1/20 0.35
NFKB1 P19838 1/20 0.35
HIF1A Q16665 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27900869 1.00 CASP1 (0.43) CASP1CYP1A2SMN1; SMN2CYP2D6PKM
SCHEMBL27918589 1.00 CASP1 (0.43) CASP1CYP1A2SMN1; SMN2CYP2D6PKM
SCHEMBL28041733 0.86 CASP1 (0.45) CASP1CYP1A2SMN1; SMN2CYP2D6PKM
SCHEMBL28041758 0.86 CASP1 (0.45) CASP1CYP1A2SMN1; SMN2CYP2D6PKM
SCHEMBL28041546 0.86 CASP1 (0.45) CASP1CYP1A2SMN1; SMN2CYP2D6PKM
Carisbamate SCHEMBL8741032 0.81 ADRB2 (0.49) CASP1CYP1A2SMN1; SMN2CYP2D6PKM
Carisbamate SCHEMBL8741086 0.81 ADRB2 (0.49) CASP1CYP1A2SMN1; SMN2CYP2D6PKM
SCHEMBL13879248 0.81 CASP1 (0.48) CASP1CYP1A2SMN1; SMN2CYP2D6PKM
Carisbamate SCHEMBL729003 0.79 AOC3 (0.49) CASP1CYP1A2SMN1; SMN2CYP2D6PKM
Carisbamate SCHEMBL1037665 0.79 AOC3 (0.49) CASP1CYP1A2SMN1; SMN2CYP2D6PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104136413-B For preventing or treat the carbanilate compound of epilepsy 比皮艾思药物研发有限公司 2016-10-26 CN claimed
CN-104136415-B Phenyl carbamate compounds for use in preventing or treating stroke 比皮艾思药物研发有限公司 2016-09-07 CN claimed
CN-105228604-A Phenyl carbamate compounds for use in preventing or treating pediatric epilepsy and epilepsy-related syndrome BIO PHARM SOLUTIONS CO LTD 2016-01-06 CN claimed
CN-105209430-A Phenyl carbamate compounds and neuroprotective compositions comprising the same BIO PHARM SOLUTIONS CO LTD 2015-12-30 CN claimed
CN-105189451-A Phenyl carbamate compound and composition for preventing or treating nerve gas-induced diseases comprising the same BIO PHARM SOLUTIONS CO LTD 2015-12-23 CN claimed
CN-105188689-A Phenyl carbamate compounds for use in preventing or treating epilepsy and epilepsy-related syndromes BIO PHARM SOLUTIONS CO LTD 2015-12-23 CN claimed
CN-105164103-A Phenyl carbamate compound and composition for preventing or treating memory loss-related disease comprising same BIO PHARM SOLUTIONS CO LTD 2015-12-16 CN claimed
CN-104870421-A Phenyl carbamate compounds for use in preventing or treating ALS BIO PHARM SOLUTIONS CO LTD 2015-08-26 CN claimed
CN-104628603-A Phenylcarbamate compound and muscle relaxant containing the same BIO PHARM SOLUTIONS CO LTD 2015-05-20 CN claimed
CN-103080079-B Phenyl carbamate compound and muscle relaxant containing phenyl carbamate compound BIO PHARM SOLUTIONS CO LTD 2015-01-21 CN claimed
CN-104169253-A Phenyl carbamate compounds for use in alleviating or treating pain BIO PHARM SOLUTIONS CO LTD 2014-11-26 CN claimed
CN-104136415-A PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO PHARM SOLUTIONS CO LTD 2014-11-05 CN claimed
CN-104136414-A PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING MULTIPLE SCLEROSIS BIO PHARM SOLUTIONS CO LTD 2014-11-05 CN claimed
CN-104136413-A PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILESY BIO PHARM SOLUTIONS CO LTD 2014-11-05 CN claimed
CN-103080079-A Phenyl carbamate compound and muscle relaxant containing phenyl carbamate compound BIO PHARM SOLUTIONS CO LTD 2013-05-01 CN claimed
CN-110478343-A Phenyl carbamate compound and comprising the compound for preventing or treating the composition of disease caused by nerve gas BIO PHARM SOLUTIONS CO LTD 2019-11-22 CN disclosed
CN-105209430-B Phenyl carbamate compounds and neuroprotective compositions comprising the same 比皮艾思药物研发有限公司 2019-09-13 CN disclosed
CN-104136415-A PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO PHARM SOLUTIONS CO LTD 2014-11-05 CN disclosed
CN-104136414-A PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING MULTIPLE SCLEROSIS BIO PHARM SOLUTIONS CO LTD 2014-11-05 CN disclosed
CN-103080079-A Phenyl carbamate compound and muscle relaxant containing phenyl carbamate compound BIO PHARM SOLUTIONS CO LTD 2013-05-01 CN disclosed