SCHEMBL2790146

SCHEMBL2790146

CCCCCCCCC=CCCCCCCCC(=O)OC(=O)Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 3/20 0.58
PTPN1 P18031 3/20 0.58
PPARG P37231 3/20 0.58
PPARD Q03181 3/20 0.58
PPARA Q07869 3/20 0.58
FAAH O00519 3/20 0.58
CYP1A2 P05177 2/20 0.58
MAPT P10636 2/20 0.58
CYP2C19 P33261 2/20 0.58
BLM P54132 2/20 0.58
HSD17B10 Q99714 2/20 0.58
FABP4 P15090 2/20 0.58
KMT2A Q03164 2/20 0.58
GMNN O75496 1/20 0.58
USP2 O75604 1/20 0.58
LMNA P02545 1/20 0.58
POLB P06746 1/20 0.58
CYP2C9 P11712 1/20 0.58
ALOX15 P16050 1/20 0.58
APEX1 P27695 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21599132 1.00 TERT (0.58) TERTPTPN1PPARGPPARDPPARA
SCHEMBL2789551 0.95 ALDH1A1 (0.61) PPARGPPARDPPARAHSD17B10FABP4
SCHEMBL25294138 0.89 TERT (0.66) TERTPTPN1PPARGPPARDPPARA
SCHEMBL25287432 0.89 TERT (0.66) TERTPTPN1PPARGPPARDPPARA
SCHEMBL25294275 0.89 TERT (0.66) TERTPTPN1PPARGPPARDPPARA
SCHEMBL25285982 0.89 TERT (0.66) TERTPTPN1PPARGPPARDPPARA
SCHEMBL25293648 0.89 TERT (0.66) TERTPTPN1PPARGPPARDPPARA
SCHEMBL25288168 0.89 TERT (0.66) TERTPTPN1PPARGPPARDPPARA
SCHEMBL25292890 0.89 TERT (0.66) TERTPTPN1PPARGPPARDPPARA
SCHEMBL23041976 0.89 TERT (0.66) TERTPTPN1PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12503483-B2 Gemcitabine amphiphile prodrugs NanoMed Holdings Pty Ltd (AU) 2025-12-23 US disclosed
US-20210238214-A1 GEMCITABINE AMPHIPHILE PRODRUGS NanoMed Holdings Pty Ltd (AU) 2021-08-05 US disclosed
EP-3784681-A1 GEMCITABINE AMPHIPHILE PRODRUGS NanoMed Holdings Pty Ltd (AU) 2021-03-03 EP disclosed
EP-2393472-B1 AMPHIPHILE PRODRUGS NanoMed Holdings Pty Ltd (AU) 2019-06-05 EP disclosed
US-8603999-B2 Amphiphile prodrugs COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2013-12-10 US disclosed
EP-2393472-A1 AMPHIPHILE PRODRUGS Commonwealth Scientific and Industrial Research Organisation (AU) 2011-12-14 EP disclosed
US-20110301114-A1 AMPHIPHILE PRODRUGS NanoMed Holdings Pty Ltd (AU) 2011-12-08 US disclosed
WO-2010063080-A1 AMPHIPHILE PRODRUGS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-06-10 WO disclosed
US-5942387-A Combinatorial process for preparing substituted thiophene libraries ELI LILLY AND COMPANY (US) 1999-08-24 US disclosed
EP-0825164-A2 Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides ELI LILLY AND COMPANY (US) 1998-02-25 EP disclosed
US-4352938-A ADHESION OF POLYPROPYLENE TO GLASS FIBERS OR TIRE CORDS TO RUBBER HERCULES INCORPORATED (US) 1982-10-05 US disclosed
US-3971743-A CROSSLINKING POLYMERS HERCULES INCORPORATED (US) 1976-07-27 US disclosed
US-3971627-A MODIFIED POLYESTER, POLYAMIDE, POLYCARBONATE, POLYOLEFIN OR RAYON TIRE CORD HERCULES INCORPORATED (US) 1976-07-27 US disclosed
US-3941751-A Epoxy-azido compounds HERCULES INCORPORATED (US) 1976-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238214-A1 GEMCITABINE AMPHIPHILE PRODRUGS GBA1, GMNN, TYMP TERT 2301/4885PTPN1 2884/4885PPARG 565/4885
US-20110301114-A1 AMPHIPHILE PRODRUGS ANXA3, ADORA3, SLC18A1 TERT 2616/4885PTPN1 1527/4885PPARG 4609/4885
US-12503483-B2 Gemcitabine amphiphile prodrugs GBA1, GMNN, TYMP TERT 2301/4885PTPN1 2884/4885PPARG 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.